-Karthik Gurumurthy

Don’t we have enough in the menu creating issues..Do we need another one?

Anyway going back to the question, any cell in the body has the potential to become malignant; thus cancer can, in fact, affect the heart. Cancer arises because of mutations in the DNA of a cell. Generally a cancerous cell undergoes several mutations before it becomes a deadly, invasive cancer. Most of these mutations occur when the cell is dividing and replicating in DNA. The only way for a cell to propagate a mutation is to divide and pass those mutations on to its daughter cells. With regards to the heart cells, however, they just go right on pumping and doing their job and don’t replicate to make new heart cells unless there has been some injury. With so little division going on in the heart, there is very little chance for mutations to occur and get passed onto daughter cells.

Now think about the types of cancer that are most common- breast, colon, and skin, among others.

Most of the cells in these tissues are replacing themselves all the time. Breast tissue is constantly affected by hormones and is always growing and shrinking. The lining of the colon is continually shedding off and being replaced. The same is true of the skin. In addition, skin and colon cells are constantly being exposed to things that induce mutations- ultraviolet rays for the skin and carcinogens in food for the colon. As a result, the likelihood of mutations is higher, and there is ample opportunity to pass these mutations on to daughter cells during cell division. That is why these cancers are common. The heart, in contrast, doesn’t get exposed to many carcinogens, just those in the blood. That combined with the fact that the heart cells do not replicate often, is why we don’t see much cancer of the heart muscle.

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